Activities

Research

RCI research is focused on and integrated with Infectious Diseases and Global Health (ID&GH), one of the research themes of Radboudumc accommodated by the research institutes Radboud Institute for Health Sciences (www.rihs.nl) and Radboud Institute for Molecular Life Sciences  (www.rihs.nl). Basic research on the study of microorganisms, host defense against infectious agents, the normal immune response and its dysregulation leading to susceptibility to infectious diseases will provide the scientific rationale and research network for translational and clinical studies to explore and develop novel diagnostic tools, therapeutic strategies and designing vaccines.

The ID&GH theme combines cutting edge research in immunology, microbiology, pharmacology, ‘omics’ and systems biology, with translational research in immunology and infectious diseases, as well as implementation research at a population level. Thus integrating research from molecule-to-man-to-population. Researchers of the theme ID&GH aim to have a significant and global impact on the control, treatment and elimination of infectious diseases. These aims will be accomplished through several complementary strategies:

  • Basic research aimed at understanding biological mechanisms will identify novel targets for diagnosis and therapy
  • Translational research will aim to identify and validate relevant biological processes in patients
  • Epidemiological research will study infections and global health at a population level

The ID&GH theme has two major research lines (Infectious Diseases and Global Health) that should not be considered as separate entities but rather as interrelated activities, which results in synergic accomplishments.
Our core activities are formed by the research activities within the expertise centres. These are supplemented by three extra themes, as outlined below:

  • Antimicrobial resistance and stewardship
  • Auto-inflammatory diseases
  • Complex orthopedic and vascular infections
  • Fever of unknown origin
  • HIV
  • Optimizing diagnostics in infectious diseases
  • Immune deficiencies
  • Improving access to health care and cost-effectiveness analysis
  • Infection prevention
  • Lyme
  • Medical Mycology
  • Optimization host defence in Infectious diseases
  • Pattern recognition and trained immunity
  • Tuberculosis and non- tuberculous mycobacterial diseases
  • Q fever
  • Tropical infectious diseases
  • Vaccine development